A Formal Total Synthesis of (-)-Oudemansin B.
نویسندگان
چکیده
منابع مشابه
Formal total synthesis of triptolide.
A new approach to the medicinally-important natural product triptolide is significantly shorter than previous syntheses, highly convergent and avoids the use of protecting groups; key features include two Diels-Alder reactions and a new deoxygenative aromatisation process.
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thesis of cephalotaxine (1), the major alkaloid of the Cephalotaxus species, because of its unique structural features and antileukemic activity of its ester derivatives, harringtonine (2) and homoharringtonine (3). So far, eight total syntheses of (6)-1 including ours have been reported and the synthesis of (2)-1 has recently been achieved by Mori’s and Nagasaka’s groups. As a part of our own ...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1992
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.40.2847